

From episode 39–50, the respective opening and ending themes are "Period" by Chemistry, and " Shunkan Sentimental" ( 瞬間センチメンタル, Shunkan Senchimentaru, lit. From episodes 51–62, the respective opening and ending themes are "Rain" ( レイン, Rein) by Sid, and "Ray of Light" by Shoko Nakagawa. Transcription: " Hagane no Renkinjutsushi" ( Japanese: 鋼の錬金術師) While episodes 63 and 64 do not use opening themes, they use "Rain" and "Hologram", respectively, for the endings. The Elric brothers, Edward and Alphonse, have already made a strong reputation for themselves despite Edward's short military career. They are called upon by the Führer King Bradley and Colonel Roy Mustang to hunt down the "Freezing Alchemist", the rogue state alchemist Isaac McDougal. Edward and Alphonse ambush and successfully capture their target.


However, Edward becomes enraged by McDougal calling him "small" and McDougal finds an opening and escapes. The Elric brothers and the state military are forced to confront McDougal again when he simultaneously activates numerous transmutation circles in Central. This creates an alchemic reaction encompassing the entire command center. Edward suspects the use of a philosopher's stone, but is unable to confirm his suspicion. Luckily, the Elric brothers, Major Alex Louis Armstrong, and Mustang succeed in thwarting McDougal's plans to bury Central in ice.
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